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Julio A Urbina Selected Research

TAK 187

4/2005Comparative efficacies of TAK-187, a long-lasting ergosterol biosynthesis inhibitor, and benznidazole in preventing cardiac damage in a murine model of Chagas' disease.
1/2003Parasitological cure of acute and chronic experimental Chagas disease using the long-acting experimental triazole TAK-187. Activity against drug-resistant Trypanosoma cruzi strains.

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Julio A Urbina Research Topics

Disease

29Chagas Disease (American Trypanosomiasis)
12/2021 - 01/2002
9Infections
12/2021 - 06/2006
3Leishmaniasis
01/2018 - 11/2005
3Persistent Infection
07/2010 - 07/2009
3African Trypanosomiasis (Nagana)
11/2007 - 11/2005
2Trichomonas Infections
06/2014 - 02/2011
2Parasitemia
01/2009 - 07/2004
2Cutaneous Leishmaniasis
11/2008 - 07/2002
2Body Weight (Weight, Body)
11/2004 - 07/2004
2Bone Resorption
03/2004 - 07/2002
1Fibrosis (Cirrhosis)
01/2020
1Invasive Fungal Infections
01/2020
1Chagas Cardiomyopathy
01/2016
1Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)
04/2015
1Sexually Transmitted Diseases (Sexually Transmitted Disease)
06/2014
1Neglected Diseases
05/2014
1Mycoses (Diseases, Fungus)
01/2011
1Inflammation (Inflammations)
07/2010
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
04/2010
1Malaria
11/2007
1Hypercholesterolemia
12/2005
1Trypanosomiasis
11/2005
1Toxoplasmosis
02/2005
1Blister (Bulla)
07/2004

Drug/Important Bio-Agent (IBA)

11benzonidazole (benznidazole)IBA
09/2021 - 04/2005
11posaconazoleFDA Link
01/2020 - 04/2007
8Pharmaceutical PreparationsIBA
01/2018 - 07/2002
6ER 30346 (ravuconazole)IBA
09/2021 - 01/2003
5NifurtimoxIBA
09/2020 - 01/2008
5SterolsIBA
05/2014 - 12/2005
4Ergosterol (Lumisterol)IBA
01/2020 - 04/2005
4EnzymesIBA
05/2014 - 01/2006
4Amiodarone (Amiodarona)FDA LinkGeneric
07/2012 - 02/2006
4Antiparasitic Agents (Antiparasitics)IBA
04/2010 - 01/2002
3TriazolesIBA
01/2018 - 01/2003
3Farnesyl-Diphosphate Farnesyltransferase (Squalene Synthase)IBA
05/2014 - 12/2005
2Metronidazole (Metric)FDA LinkGeneric
06/2014 - 02/2011
2Anti-Arrhythmia AgentsIBA
07/2012 - 01/2011
2cruzipainIBA
07/2010 - 01/2002
23- ((2- benzyl- 6- (3- methoxypropyloxy)pyridin- 3- yl)ethynyl)quinuclidin- 3- olIBA
11/2008 - 07/2004
2HexokinaseIBA
04/2007 - 01/2006
2TAK 187IBA
04/2005 - 01/2003
2Risedronic Acid (Actonel)FDA LinkGeneric
03/2004 - 03/2004
2farnesyl pyrophosphate (farnesyl diphosphate)IBA
03/2004 - 03/2004
2Diphosphonates (Bisphosphonates)IBA
03/2004 - 07/2002
1Biomarkers (Surrogate Marker)IBA
12/2021
1Fibronectins (Fibronectin)IBA
01/2020
1Laminin (Merosin)IBA
01/2020
1Drug CombinationsIBA
01/2013
1ProdrugsIBA
12/2012
1Sterol 14-DemethylaseIBA
12/2012
114-alpha Demethylase InhibitorsIBA
12/2012
1Thomsen-Friedenreich antibodiesIBA
07/2012
1CytochromesIBA
01/2011
1Cysteine Proteases (Cysteine Protease)IBA
07/2010
1AntibodiesIBA
07/2010
1AzolesIBA
04/2009
1CholesterolIBA
11/2008
1Growth InhibitorsIBA
11/2008
1AllylamineIBA
01/2008
1Terbinafine (Lamisil)FDA LinkGeneric
01/2008
1Squalene Monooxygenase (Squalene Epoxidase)IBA
01/2008
1QuinuclidinesIBA
11/2007
1Adenosine Triphosphate (ATP)IBA
04/2007
1diphosphoric acid (pyrophosphoric acid)IBA
04/2007
1Glucose (Dextrose)FDA LinkGeneric
04/2007
1Interleukin-12 (IL 12)IBA
04/2007
1Interferon-gamma (Interferon, gamma)IBA
04/2007
1miltefosine (Impavido)IBA
11/2005
1Paromomycin (Paromomycin Sulfate)FDA LinkGeneric
11/2005
1Amphotericin B (Amphotericin)FDA LinkGeneric
11/2005
1Eflornithine (Ornidyl)FDA Link
11/2005
1Folic Acid AntagonistsIBA
02/2005
1albaconazoleIBA
11/2004
1ChromatinIBA
07/2004
1Terpenes (Terpenoids)IBA
03/2004
14-phenoxyphenoxyethyl thiocyanateIBA
06/2003
1Kinetoplast DNA (kDNA)IBA
07/2002
1Pamidronate (Aredia)FDA LinkGeneric
07/2002
1Cathepsin LIBA
01/2002
1NitroimidazolesIBA
01/2002
1Peptide Hydrolases (Proteases)FDA Link
01/2002

Therapy/Procedure

7Therapeutics
12/2021 - 07/2002
6Drug Therapy (Chemotherapy)
12/2021 - 01/2002